- Fox has the MLB playoffs
- NBC is new with My Name Is Earl, the series premiere of Kath and Kim, The Office, the premiere of Saturday Night Live Weekend Update Thursday, and ER
- CBS is new with Survivor, the season premiere of CSI, and the series premiere of Eleventh Hour
- ABC is new with Ugly Betty, Grey's Anatomy, and the series premiere of Life on Mars
- The CW is new with Smallville and Supernatural
- Bravo is new with Tabatha's Salon Takeover and Tim Gunn's Guide to Style
- MTV has True Life
- VH1 has 100 Greatest Teen Stars
- FX is new with It's Always Sunny in Philadelphia and the premiere of Testees
- Comedy Central is new with The Daily Show With Jon Stewart and The Colbert Report
- Late-night highlights include Bill Murray and Beck on Late Show With David Letterman on CBS; Mark Wahlberg, Rachel Maddow, and Rachael Yamagata on The Tonight Show With Jay Leno on NBC; and Dennis Quaid, Lance Mackey, and Sarah McLachlan on Late Night With Conan O'Brien on NBC

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